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New Drug Could ‘Cure’ Hair Loss In ‘Six Weeks’

bruce willisBald people have been given fresh hope after an eczema drug restored hair growth in a teenage girl with long-standing alopecia. Doctors told how their 13-year-old patient, who has alopecia totalis – a total lack of scalp hair – as well as eczema, experienced ‘significant’ hair regrowth while being treated with dupilumab, a drug marketed

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Bald people have been given fresh hope after an eczema drug restored hair growth in a teenage girl with long-standing alopecia.

Doctors told how their 13-year-old patient, who has alopecia totalis – a total lack of scalp hair – as well as eczema, experienced ‘significant’ hair regrowth while being treated with dupilumab, a drug marketed under the brand name Dupixent.

The unexpected side-effect came from treatment with dupilumab, which is approved for the treatment of moderate to severe eczema, also called atopic dermatitis.

Study senior author Dr Maryanne Makredes Senna, of Massachusetts General Hospital (MGH) in the US, said:

We were quite surprised since this patient hadn’t grown scalp hair since the age of two, and other treatments that can help with hair loss did not in her case.

As far as we know, this is the first report of hair regrowth with dupilumab in a patient with any degree of alopecia areata.

In addition to longstanding alopecia, this girl had also experienced extensive, treatment-resistant eczema since the age of seven months.

Treatment with prednisone and methotrexate, medications that can suppress the overactive immune system, led to limited improvement in her eczema but no hair regrowth and was therefore discontinued.

In July 2017 she began to be treated with weekly injections of dupilumab, which had recently received official approval.

Here are two pictures of a patient, six weeks and 11 months after treatment:

Hair growthSWNS
Hair growthSWNS

After six weeks of treatment, which led to significant improvement in eczema symptoms, she also noticed that fine light hairs called vellus hairs were appearing on her scalp.

After seven months of dupilumab treatment, the girl had grown a ‘significant’ amount of the pigmented hair that typically grows on the scalp.

Because of a change in her insurance coverage, she had to discontinue dupilumab for a two-month period, during which she noticed shedding of the recently regrown hair.

But after she could resume treatment in April this year, the hair growth resumed and has continued.

Dr Senna explained that dupilumab’s mechanism of targeting a key immune system pathway known to be overactive in eczema could explain its action against alopecia, since recent studies have suggested other elements of the same pathway may induce autoimmune hair loss.

She added:

Right now, it’s hard to know whether dupilumab could induce hair growth in other alopecia patients, but I suspect it may be helpful in patients with extensive active eczema and active alopecia areata.

We’ve submitted a proposal for a clinical trial using dupilumab in this patient population and hope to be able to investigate it further in the near future.

Wow. It’s a start isn’t it? Let’s hope the research continues to grow.

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Stephen Hawking Had One Last Warning About The End Of Humanity Before He Died

Stephen AIn a collection of essays which will be published posthumously, the late Professor Stephen Hawking made an eerie prediction regarding the future of humanity.

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Stephen Hawking predicted a new 'superhuman' race.

In a collection of essays which will be published posthumously, the late Professor Stephen Hawking made an eerie prediction regarding the future of humanity.

Professor Hawking, who died in March 2018 at the age of 76, suggested there would be a new superhuman race, on account of the wealthy elite editing their own DNA and that of their children; manipulating factors such as memory, resistance to disease, cognitive ability and longevity.

The legendary theoretical physicist believed advances in genetic engineering could lead to a new superhuman species, ultimately resulting in the destruction of the rest of humanity.

In an extract of upcoming essay collection – which has been printed in The Sunday Times – Professor Hawking wrote:

I am sure that during this century people will discover how to modify both intelligence and instincts such as aggression,

Laws will probably be passed against genetic engineering with humans. But some people won’t be able to resist the temptation to improve human characteristics, such as memory, resistance to disease and length of life.

Those who are left unedited – i.e. us regular Joes – would face serious problems should this frightening prediction come to pass, helpless to even consider keeping up with the superhumans.

Speaking with the concern for humanity which endeared him to so many, Professor Hawking continued:

Once such superhumans appear, there will be significant political problems with unimproved humans, who won’t be able to compete,

Presumably, they will die out, or become unimportant. Instead, there will be a race of self-designing beings who are improving at an ever-increasing rate.

Frighteningly, Professor Hawking was drawing from existing techniques which are sparking debate within the scientific community.

DNA-editing system Crispr-Cas9, was invented back in 2012, allowing for the modification of harmful genes or for the addition of new ones. Children at London’s Great Ormond Street Hospital who have incurable cases of leukaemia have undergone gene-editing.

However, some scientists believe parents wouldn’t run the risk of modifying genes for fear of side effects.

According to The Sunday Times, many scientist have welcomed Professor Hawking’s predictions, including professor of climate science at University College London, Chris Rapley.

Professor Rapley said:

Humans have arguably reached a critical moment,

We have moved beyond affecting the planet at the landscape scale to interfering with its very metabolism at the global scale. All the indications are that the limitations of our brains, both individually and collectively, leave us incapable of addressing the challenge. On this basis the future looks desperately gloomy.

Even after his death, Professor Hawking’s writings live on; encouraging each and every one of us to think about the future in a considerate and responsible way.

Brief Answers to the Big Questions by Professor Stephen Hawking will be available to purchase in bookshops from October 16, 2018. The perfect Christmas present for a brainy friend or family member.

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Simon Cowell Donates £50,000 For Boy To Get Cancer Treatment In The US

KIDA COWELL WEBWhile Simon Cowell has a reputation for being brutally honest during talent shows, he also has a caring side. After hearing about a young boy who needed money to travel to the US for vital cancer treatment, the music mogul announced he would be donating an amazing £50,000 to the cause. With the family needing

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While Simon Cowell has a reputation for being brutally honest during talent shows, he also has a caring side.

After hearing about a young boy who needed money to travel to the US for vital cancer treatment, the music mogul announced he would be donating an amazing £50,000 to the cause.

With the family needing to raise a total of £500,000 to send four-year-old Zac Oliver, from Broseley, to America, Cowell has also urged X Factor fans to donate.

zac cancer simon cowellZachariah's fight against Acute Lymphoblastic Leukaemia/Facebook

Suffering from an extremely rare form of leukaemia known as Near Haploid, chemotherapy hasn’t had an effect on Zac’s cancer after four months of treatment leaving the family looking for alternatives.

Reading about clinical trials in America which have saved lives, although they are still classed as being experimental, Zac’s family are hoping to send him to Philadelphia for CAR-T therapy.

On a crowdfunding page which has been set up for Zac, his family wrote:

There is a price on our little boy’s life and we can’t afford it. This huge amount is only achievable with everyone’s help. Together we can give him the chance of a first day of school, riding a bike without stabilisers, falling in love, getting married, travelling, just growing up.

We are striving to get Zac the best possible treatment to give him the best chance of survival and a fighting chance for life, Zachariah is only four so he has a whole life to yet live.

Philadelphia Children’s hospital have Quoted $625,000 to carry out the treatment, the original Quote was $1,250,000 but this was reduced with the subsidy of some treatments. We would also have to relocate for a sustained period of time of which we are not sure yet.

Please help us get him to America and give him the best fighting chance.

With the family adding that ‘as of October 12’ they have so far raised £395,000, hopefully it won’t be long until they can hit their target.

Cowell’s £50,000 will certainly help and he even filmed a short video for the family to share which calls on people to donate.

He said:

This boy is four years old and needs money to get to America to get the help he needs.

So, I want you to go onto Zac Oliver’s JustGiving page and whatever you can donate will make a difference.

And because I don’t like those who tell people to do something and don’t do it themselves, I’m going to donate £50,000 so we’re going to get there.

You can watch the video here:

Thank you to Simon Cowell for doing such an amazing job at supporting our cause. I explained to Zac that Simon has helped to pay for his special medicine. Zac said 'thanks si' lol little does he know exactly what this actually means and how much closer we really are to getting him to the US. Xxxx

Posted by Hannah Oliver-Willets on Friday, 12 October 2018

Hopefully Zac will get to America and that the treatment is successful! We certainly wish Zac and his family all the best in the future.

If you want to donate to Zac’s cause, you can do so on his JustGiving page.

If you’ve been affected by any of these issues, and want to speak to someone in confidence contact Macmillan’s Cancer Support Line on 0808 808 00 00 (Monday – Friday, 9am – 8pm).

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Today Is National Be Bald And Be Free Day

bald day wwebBald is beautiful and although we remember this every day of the year, October 14 dedicates itself to celebrating the naked crown. That means today is officially Be Bald and Be Free Day, sometimes referred to as Bald and Free Day, an annual event which is celebrated worldwide. Whether you are bald by choice or

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Bald is beautiful and although we remember this every day of the year, October 14 dedicates itself to celebrating the naked crown.

That means today is officially Be Bald and Be Free Day, sometimes referred to as Bald and Free Day, an annual event which is celebrated worldwide.

Whether you are bald by choice or not, man or woman, today is the day to leave your wig or hat off and embrace your baldness, showing off your scalp.

cara delevingne baldGetty

Although it is not clear how Be Bald and Be Free Day started, why not have a national day to celebrate the chrome dome in all of its glory.

Baldness is certainly not a sign of weakness, in fact it is the opposite symbolising strength.

Just look at notable bald men and women including Sinead O’Connor, Mahatma Ghandi and Bruce Willis. I don’t think anyone would be quick to label these people as ‘weak’!

People have been taking to social media throughout the day to share their bald selfies.

Shaun Staunton took to Instagram posting a photo after he ‘braved the shave’:

Although this national day doesn’t have a huge amount of awareness, I sympathise with those going through hair loss themselves. I know there are far worse things that can happen to you but for me the only way I can really describe it is as if your body has betrayed you.

And as such I wanted to share the day I decided to shave my hair off for anyone else struggling with hair loss too.

This picture was taken yesterday (at a Roman Fort) and I still prefer my head cleanly shaved. So in appreciation for Be Bald and Be Free day (and when in Rome, of course) I bring you ‘The day I shaved my hair off’.

Jennifer shared an inspiring post on her Instagram writing:

Self confidence is the key to your happiness!!! Happy National #BeBaldAndFreeDay. Never forget to be who YOU are, and always listen to your heart.

There’s already someone else, so why not show the world a lil’ something unique? Feed your passion. Love y’all!

One Twitter user even shared a photo of their hairless cat who is also proud to be bald:

October 14th is officially known as Be Bald And Free Day. It’s a special celebration for humans of the less hirsute variety, but it’s also a smart prompt to take a peek into the very distinctive world of hairless cats.

According to a study, bald men are seen to be much stronger, confident and dominant compared to those with locks of hair.

Psychoanalyst Steve McKeown, founder of MindFixers and owner of The McKeown Clinic, spoke to UNILAD about how the study was conducted and the results.

He said:

In a study, researchers have found there are positives gains psychologically, where bald men have been perceived more dominant, more confident and more masculine, stronger and taller.

The study included a group of participants who would score photos of men with full heads of hair and another group that would score the same men, but with their hair computer digitally removed and because only their hair was adjusted any dissimilarities between the groups had to be due to baldness.

Researchers also wanted ascertain whether this idea was consistent even when men were described in words with no photos were studied. This time they used men whereby their hair was just thinning but not completely bald.

The researchers noted bald men were again perceived as more confident, dominant, masculine and stronger but men who were thinning or trying to hold on were worse off opposed to bald men or those with a full head of hair.

So happy Be Bald and Be Free Day folks!

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